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Year : 2016  |  Volume : 2  |  Issue : 1  |  Page : 10-13

Periodontal vaccine: A new vista in periodontology - A review

Department of Periodontology, Subharti Dental College and Hospital, Meerut, Uttar Pradesh, India

Correspondence Address:
D Deepa
Department of Periodontology, Subharti Dental College and Hospital, Meerut - 250 005, Uttar Pradesh
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/2455-3069.184117

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The infectious etiology of periodontitis is complex. Due to its high prevalence rate, this disease has created an interest in finding a solution in the form of vaccines. Vaccination is the best known and the most important application of immunological principles to human health. The complexity of the periodontopathic bacteria might be a problem in the determination of antigens, thus complicating the development of periodontal vaccine. An attempt to review the literature on periodontal vaccine, including active immunization: Whole bacterial cells, sub-unit vaccines, synthetic peptides as antigens; passive immunization: Murine monoclonal antibodies and plantibodies; and genetic immunization: Plasmid vaccines, live, viral vector vaccines, has been done in this study.

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