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Year : 2016  |  Volume : 2  |  Issue : 2  |  Page : 136-138

Myasthenia gravis: A rare presentation with absent ocular symptoms

1 Department of Pharmacology, Institute of Post Graduate Medical Education and Research, Kolkata, West Bengal, India
2 Department of Pediatrics, Medical College, Dreamland Nursing Home, Kolkata, West Bengal, India
3 Medical Director and Incharge - Intensive Care Unit, Dreamland Nursing Home, Kolkata, West Bengal, India

Correspondence Address:
Sandeep Lahiry
Department of Pharmacology, Institute of Post Graduate Medical Education and Research, 244B, A.J.C. Bose Road, Kolkata - 700 020, West Bengal
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/2455-3069.198373

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Myasthenia gravis (MG) is an autoimmune disorder in which there is antibody formation against acetylcholine (ACh) nicotinic postsynaptic receptors at the neuromuscular junction of skeletal muscles. Bulbar muscle paralysis is common, along with weakness in head and neck flexion. Extraocular muscle weakness or ptosis is the initial presentation in 50% cases and >90% cases during illness. It is usually treated with medications such as ACh-esterase inhibitors or immunosuppressants. Selected cases require thymectomy. Here, we present the case of a 32-year-old woman with MG, who presented with an unexplained respiratory failure in the absence of typical ocular symptoms. The diagnosis was based on clinical suspicion and specific laboratory tests. She was stabilized with mechanical ventilation and subsequently treated with immunoglobulin therapy and thymectomy.

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