| ORIGINAL ARTICLE |
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| Year : 2017 | Volume
: 3
| Issue : 2 | Page : 84-87 |
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Evaluation of antidiabetic property of quail egg on alloxan-induced diabetes mellitus in Wistar albino rats
Amarachi Agbafor1, David Arome2, Wilson Goodness Oluebube1
1 Department of Biochemistry, Michael Okpara University of Agriculture, Umudike, Abia, Nigeria
2 Department of Public Health, School of Public Health, Texila American University, Georgetown, Guyana
Correspondence Address:
David Arome
School of Public Health, Texila American University, Georgetown
Guyana
 Source of Support: None, Conflict of Interest: None  | Check |
DOI: 10.4103/jcrsm.jcrsm_32_17
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Background: Alloxan-induced hyperglycemia has been a useful experimental model to study activity of hypoglycemic agents. Alloxan has been utilized in the diabetes model due to its ability to produce a high percentage of the endogenous beta cells destruction.
Objective: The principal objective of the study was to evaluate the antidiabetic property of quail egg on alloxan-induced diabetes in Wistar albino rats.
Materials and Methods: Freshly, prepared quail egg of 0.5, 1.0, and 1.5 ml and reference standard drug of metformin 10 mg/kg were used in the study, administered through oral route. The antidiabetic property of the quail egg was evaluated using alloxan-induced diabetes in Wistar albino model.
Results: The quail egg-treated groups (1.0 and 1.5 ml) exhibited considerable significant (P < 0.05) antidiabetic property with drastic reduction in the blood glucose level. There was a significant reduction in the blood glucose levels in the quail egg-treated groups at day 7 and 14, respectively. The quail egg-treated group of 1.5 ml showed better antidiabetic activity characterized with a significant reduction of blood glucose level compared to the positive group which received the standard reference drug metformin monohydrate 10 mg/kg.
Conclusion: The research findings of the study clearly showed that quail egg possesses an antidiabetic property. |
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