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 Table of Contents  
LETTER TO EDITOR
Year : 2021  |  Volume : 7  |  Issue : 2  |  Page : 151

Evaluation of carotid intima-media thickness in primary hypertensive patients using B-mode ultrasound: Cross-sectional study


Department of Paediatrics, Al-Kindy College of Medicine, University of Baghdad, Baghdad, Iraq

Date of Submission01-Mar-2021
Date of Decision25-May-2021
Date of Acceptance26-Aug-2021
Date of Web Publication30-Dec-2021

Correspondence Address:
Mahmood Dhahir Al-Mendalawi
P.O. Box 55302, Baghdad Post Office, Baghdad
Iraq
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/jcrsm.jcrsm_1_21

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How to cite this article:
Al-Mendalawi MD. Evaluation of carotid intima-media thickness in primary hypertensive patients using B-mode ultrasound: Cross-sectional study. J Curr Res Sci Med 2021;7:151

How to cite this URL:
Al-Mendalawi MD. Evaluation of carotid intima-media thickness in primary hypertensive patients using B-mode ultrasound: Cross-sectional study. J Curr Res Sci Med [serial online] 2021 [cited 2022 Jun 28];7:151. Available from: https://www.jcrsmed.org/text.asp?2021/7/2/151/334446



Sir,

I read with interest the case–control study by Mustafa et al.[1] published in the July–December 2020 issue of the Journal of Current Research in Scientific Medicine. On using the B-mode ultrasound, the authors explored the correlation between hypertension (HTN) and elevation of the intima-media thickness (IMT) of both the right and left common carotid arteries (CCAs) among a cohort of Sudanese patients with HTN. They found that the IMT in the CCAs was higher in the hypertensive patients than in the controls (P < 0.001). Moreover, IMT of the right and left CCAs significantly increased with the increment in the duration of HTN (P = 0.023 and 0.031, respectively).[1] The authors addressed the following study limitations: inadequate sample size; unavailability of certain demographic data such as body mass index; and the lack of related laboratory tests such as cholesterol, low-density protein, and high-density lipoprotein levels in the case group.[1] I assume that the following methodological limitation might be also relevant. It is worthy to mention that to accurately assess IMT for a particular population, there is a need to refer to the reference intervals (RIs) of IMT for that population. Indeed, there are certain determinants of RI of IMT such as gender, age, smoking, body mass index, cholesterol, blood pressure, and genetic factors.[2] Accordingly, various population-specific RIs of IMT have been constructed to be used in the clinical settings and researches centers.[3],[4] Interestingly, Sudan is among pioneer countries that have already formulated their own RI of IMT.[5] Regrettably, it was not explicit whether Mustafa et al.[1] employed Sudanese or foreign RI of IMT in the study methodology. Hence, such methodological limitation might add further suspicions on the study results.

Financial support and sponsorship

Nil.

Conflicts of interest

There are no conflicts of interest.



 
  References Top

1.
Mustafa R, Gameraddin M, Gareeballah A. Evaluation of carotid intima-media thickness in primary hypertensive patients using B-mode ultrasound: Cross-sectional study. J Curr Res Sci Med 2020;6:84-8.  Back to cited text no. 1
  [Full text]  
2.
Zannad F, Sass C, Visvikis S. Environmental and genetic determinants of intima-media thickness of the carotid artery. Clin Exp Pharmacol Physiol 2001;28:1007-10.  Back to cited text no. 2
    
3.
Grau M, Subirana I, Agis D, Ramos R, Basagaña X, Martí R, et al. Carotid intima-media thickness in the Spanish population: Reference ranges and association with cardiovascular risk factors. Rev Esp Cardiol (Engl Ed) 2012;65:1086-93.  Back to cited text no. 3
    
4.
Mirza W, Arain MA, Ali A, Bari V, Ali MK, Fatima K. Carotid intima media thickness percentiles for Pakistani population. J Coll Physicians Surg Pak 2017;27:584-6.  Back to cited text no. 4
    
5.
Mahmoud MZ. Sonography of common carotid arteries' intima: Media thickness in the normal adult population in Sudan. N Am J Med Sci 2013;5:88-94.  Back to cited text no. 5
    




 

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